Postdoctoral Research Associate
St. Jude Children’s Research Hospital, Department of Structural Biology
St. Jude Children’s Research Hospital is seeking highly motivated candidates to join the Department of Structural Biology as a supported Postdoctoral Research Associate to drive new research directions in the Blanchard laboratory, including quantitative biophysical methods to explore clinically important biological systems at the single-molecule scale. Such pursuits will be carried out in collaboration with the Single-Molecule Imaging Center (SMC), which operates state-of-the-art fluorescence imaging technologies, including custom-built total internal reflection fluorescence (TIRF) and confocal time-correlated single-photon counting (TCSPC) microscopes. Our highly interdisciplinary, collaborative and mission-driven environment requires team-oriented individuals with strong leadership skills and the vision and creativity to successfully pursue scientific advances.
· Assume leadership positions in one or more research directions to reveal the mechanistic underpinnings of clinically important biological systems, such as ribosome-catalyzed protein synthesis, membrane protein transport/signaling, and host-virus interactions, with a special emphasis on mammalian systems. These efforts will benefit from collaborative interactions with St. Jude’s protein technology and Cryo-EM/NMR and X-Ray Centers.
· Be agile in learning and utilizing the most appropriate assays to answer the biological question at hand.
· Utilize the cadre of single-molecule fluorescence instrumentation within the SMC – or help design and construct new instrumentation – to test hypotheses and rigorously quantify results, including model building and statistical analysis.
· Regularly present research findings in a clear, concise manner to both general and specialized audiences.
· Regularly prepare high-quality manuscripts of findings for publication.
· Assist in training and mentoring graduate students, post-docs and visiting scientists.
· Ph。D。 in life science or other physical science。
· Experience with quantitative biophysical and techniques, such as fluorescence imaging/spectroscopy, force spectroscopy, or single-channel electrophysiological recordings encouraged.
· Practical experience with protein and/or nucleic acid biochemistry techniques, such as protein expression/purification/labeling and nucleic acid modification/manipulation/purification preferred.
· Expert ability to distill and convey complex information in a clear and concise manner both verbally and in writing.
Qualified applicants should apply for job 42633 at http://bit.ly/Nature42633
Roger Altman, Director of Single-Molecule Lab Operations
St。 Jude Children’s Research Hospital
Department of Structural Biology
262 Danny Thomas Place
Memphis, TN 38105